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1.
J Am Acad Orthop Surg ; 32(9): e434-e442, 2024 May 01.
Article in English | MEDLINE | ID: mdl-38489764

ABSTRACT

INTRODUCTION: Extra-articular juxtaphyseal fractures of the proximal phalanx are among the most common finger fractures in children. Immobilization of the digit for 3 to 4 weeks after reduction of the fracture is the current standard of care. The purpose of this retrospective study was to evaluate outcomes after intervention among pediatric proximal phalanx base fractures and establish radiographic criteria to guide management. METHODS: A multi-institutional retrospective review of skeletally immature patients treated for proximal phalanx juxtaphyseal fractures between 2002 and 2019 was conducted. Variables collected included Salter-Harris classification; initial, postreduction, early follow-up, and final angulation and displacement on the posterior-anterior and lateral radiographs; clinical rotational deformity at final follow-up; and method of treatment. Exclusion criteria included less than 3 weeks of follow-up; Salter-Harris III, IV, and V fractures; inadequate medical record details; and missing radiographs. RESULTS: Six hundred thirty-four fractures meeting the inclusion criteria were categorized into no reduction, closed reduction (CR), and surgical (OP) groups. Only CR and OP groups saw large decreases in angulation by 11.8° CR (95% confidence interval, 10.1 to 13.6) and 19.0° OP (95% confidence interval, 8.7 to 29.3). Closed reduction patients had a mean coronal angulation value of 6.1° at post-reduction, which was maintained with immobilization to 5.8° at final follow-up. At final follow-up, scissoring was noted, three in the no reduction and three in the CR group for an overall 0.93% rotational malalignment rate. DISCUSSION: Extra-articular proximal phalanx juxtaphyseal fractures rarely require surgical management and can typically be treated with or without CR, based on the degree of deformity, in the emergency department or clinical setting. Low rates of documented sequelae after nonsurgical management were seen in this cohort, allowing for establishment of treatment parameters that can result in clinically insignificant angular and rotational deformity. LEVEL OF EVIDENCE: Therapeutic IV.


Subject(s)
Finger Injuries , Finger Phalanges , Fractures, Bone , Humans , Child , Retrospective Studies , Finger Phalanges/diagnostic imaging , Fractures, Bone/diagnostic imaging , Fractures, Bone/surgery , Finger Injuries/therapy , Fracture Fixation, Internal/methods , Treatment Outcome
2.
Injury ; 55(4): 111441, 2024 Apr.
Article in English | MEDLINE | ID: mdl-38430751

ABSTRACT

INTRODUCTION: Phalangeal fractures are the most common fractures of the hand and in particular the proximal phalanx of the long fingers is the most involved. These fractures can ben conservatively managed but, when the fracture pattern is considered unstable, surgical treatment is recommended. However, there is no consensus in literature about the proper surgical option for extra-articular proximal phalanx fractures. MATERIAL AND METHODS: We compared clinical and radiographical results after treatment of 75 cases of extra-articular proximal phalanx fractures using three different surgical techniques: closed reduction and internal fixation (CRIF) with Kirschner wires (G1 group), open reduction internal fixation (ORIF) with plates and screws or lag screws (G2 group), and closed reduction and intramedullary screw fixation (CRIMEF)(G3 group). RESULTS: We found no significant differences in term of union rate and time to fracture healing between the three groups. However, we found a significant reduction in time to return at work and in TAM at the final follow-up examination in G3 group (treated with CRIMEF) when compared with both G1 and G2. No differences in complications rate were found between three groups. DISCUSSION: The surgical variability in the management of extra-articular phalanx fractures create lacks on standard guide for treatment. CONCLUSIONS: In conclusion, our results showed good clinical and radiographical results with all the three surgical options. However, the closed reduction and internal fixation with intramedullary screws (CRIMEF) seems to be better in terms of time to return to work and TAM at the final follow-up, probably due to good primary stability and little risk of soft tissue adherence development.


Subject(s)
Finger Phalanges , Fractures, Bone , Humans , Fractures, Bone/diagnostic imaging , Fractures, Bone/surgery , Fracture Fixation, Internal/methods , Bone Screws , Bone Wires , Finger Phalanges/diagnostic imaging , Finger Phalanges/surgery , Hand
3.
J Hand Surg Asian Pac Vol ; 29(2): 156-159, 2024 Apr.
Article in English | MEDLINE | ID: mdl-38494161

ABSTRACT

Congenital dorsal curvature of the distal phalanx has been previously described as 'reverse Kirner' or 'ski-jump' deformity. This report describes bilateral occurrence in the thumbs. A 13-year-old male presented with difficulty caring for his thumbnails and in picking up small objects. Examination showed dorsal curvature of the distal phalanges of both thumbs, with greater curvature of the right side. Radiographs showed wedge-shaped epiphyses and dorsal curvature without coronal plane deviation of the distal phalanges. There was objective and subjective decrease in function associated with lateral pinch and tripod grasp. The reported aetiopathogenesis for Kirner deformity cannot explain the observed dorsal curvature. The bilateral nature makes a secondary physeal cause unlikely and suggests an embryologic basis. Due to the noticeable deficits in function, operative intervention may be warranted. Level of Evidence: Level V (Therapeutic).


Subject(s)
Finger Phalanges , Hand Deformities, Congenital , Male , Humans , Adolescent , Thumb/surgery , Finger Phalanges/diagnostic imaging , Finger Phalanges/surgery , Hand Deformities, Congenital/surgery , Radiography
5.
Hand Surg Rehabil ; 43(2): 101634, 2024 Apr.
Article in English | MEDLINE | ID: mdl-38185365

ABSTRACT

We report a case of a 57-year-old woman who presented a rapidly progressing swelling at the base of her right 4th finger, with imaging revealing non-specific lesions suggestive of a malignant tumoral process. Following imaging, resection-biopsy revealed a non-caseating granulomatous inflammatory infiltrate suggesting sarcoidosis. Digital sarcoidosis is an uncommon presentation of the disease, especially in the early stages and without systemic symptoms. Early diagnosis and treatment are advised in order to prevent future complications.


Subject(s)
Finger Phalanges , Sarcoidosis , Humans , Female , Sarcoidosis/diagnosis , Sarcoidosis/diagnostic imaging , Sarcoidosis/pathology , Middle Aged , Finger Phalanges/diagnostic imaging , Finger Phalanges/pathology , Magnetic Resonance Imaging
6.
J Hand Surg Eur Vol ; 49(1): 106-108, 2024 01.
Article in English | MEDLINE | ID: mdl-37666237

ABSTRACT

Clinodactyly can be produced by a longitudinal epiphyseal bracket that generates either a 'delta' or 'trapezoidal' phalanx. We present a case with a 15-year follow-up of bilateral clinodactyly of the little finger, to emphasize a 'wait-and-see' approach as self-remodelling of his phalanges occurred during growth.


Subject(s)
Finger Phalanges , Hand Deformities, Congenital , Humans , Follow-Up Studies , Finger Phalanges/diagnostic imaging , Fingers , Epiphyses , Hand Deformities, Congenital/diagnostic imaging , Hand Deformities, Congenital/surgery
7.
Instr Course Lect ; 73: 305-324, 2024.
Article in English | MEDLINE | ID: mdl-38090906

ABSTRACT

A comprehensive analysis of the assessment, diagnosis, and management of phalangeal fractures and fingertip injuries should emphasize the importance of achieving the right balance between undertreatment and overtreatment. Phalangeal injuries are complex, requiring an in-depth understanding of hand anatomy, fracture patterns, and treatment options to optimize patient outcomes. A thorough examination of proximal and middle phalangeal fractures and fingertip injuries, including those to the nail bed and distal phalanx, is important. A systematic approach to addressing the most prevalent injuries in this category should be implemented while highlighting the need for patient-specific approaches to treatment and a multidisciplinary perspective to ensure the best possible outcomes for patients.


Subject(s)
Finger Injuries , Finger Phalanges , Fractures, Bone , Humans , Fractures, Bone/diagnostic imaging , Fractures, Bone/surgery , Finger Injuries/diagnostic imaging , Finger Injuries/surgery , Fracture Fixation, Internal , Finger Phalanges/diagnostic imaging , Finger Phalanges/injuries
8.
Instr Course Lect ; 73: 497-510, 2024.
Article in English | MEDLINE | ID: mdl-38090920

ABSTRACT

Phalangeal fractures are extremely common in the pediatric and adolescent populations. The incidence of phalangeal fractures peaks in children ages 10 to 14 years, corresponding to the age in which children begin contact sports. Younger children are more likely to experience crush injuries, whereas older children often sustain phalangeal fractures during sports. The physis is particularly susceptible to fracture because of the biomechanically weak nature of the physis compared with the surrounding ligaments and bone. Phalangeal fractures are identified through a thorough physical examination and are subsequently confirmed with radiographic evaluation. Management of pediatric phalangeal fractures is dependent on the age of the child, the severity of the injury, and the degree of fracture displacement. Nondisplaced fractures are often managed nonsurgically with immobilization, whereas unstable, displaced fractures may require surgery, which is often a closed rather than open reduction and percutaneous pinning.


Subject(s)
Finger Injuries , Finger Phalanges , Fracture Fixation, Intramedullary , Fractures, Bone , Sports , Adolescent , Child , Humans , Finger Phalanges/diagnostic imaging , Finger Phalanges/injuries , Finger Phalanges/surgery , Fractures, Bone/diagnostic imaging , Fractures, Bone/surgery
9.
Rev. clín. med. fam ; 16(3): 298-300, Oct. 2023. ilus
Article in Spanish | IBECS | ID: ibc-226767

ABSTRACT

La acro-osteólisis es un hallazgo radiológico infrecuente caracterizado por una reabsorción o destrucción ósea que afecta típicamente a las falanges distales de la mano.Sus causas son múltiples. Puede estar asociada a enfermedades sistémicas, tener un origen familiar, ser idiopática o secundaria a agentes externos, por lo que el patrón radiográfico, la edad del paciente y una buena historia clínica serán claves para llegar a su diagnóstico etiológico.Presentamos el caso de una mujer de 40 años que consulta por dolor de aproximadamente 1 año de evolución a nivel de la región interfalángica distal del primer y segundo dedo de la mano derecha. Entre las pruebas complementarias realizadas durante el estudio, destaca la radiografía simple de la mano, donde se observa una reabsorción parcial en banda de la región media de la falange distal del primer y segundo dedo, compatible con acro-osteólisis.(AU)


Acro-osteolysis is a rare radiological finding characterized by bone resorption or destruction that typically affects the distal phalanges of the hand.There are many causes. The condition can be associated with systemic diseases, have a family origin or be idiopathic or secondary to external agents. Therefore, the radiographic pattern, the patient’s age in addition to a good clinical history will be key to diagnosing its aetiology.We report the case of a 40-year-old woman who consulted for pain of approximately one year clinical course at the level of the distal interphalangeal region of the first and second fingers of the right hand. Among the complementary test performed during the study the x-ray revealed a band-like partial resorption in the middle region of the distal phalanx of the first and second fingers, compatible with acro-osteolysis.(AU)


Subject(s)
Humans , Female , Middle Aged , Acro-Osteolysis/diagnostic imaging , Finger Phalanges/diagnostic imaging , Radiography , Inpatients , Physical Examination
10.
Int. j. morphol ; 41(4): 1267-1272, ago. 2023. ilus, tab
Article in English | LILACS | ID: biblio-1514354

ABSTRACT

SUMMARY: In the study, it was aimed to predict sex from hand measurements using machine learning algorithms (MLA). Measurements were made on MR images of 60 men and 60 women. Determined parameters; hand length (HL), palm length (PL), hand width (HW), wrist width (EBG), metacarpal I length (MIL), metacarpal I width (MIW), metacarpal II length (MIIL), metacarpal II width (MIIW), metacarpal III length (MIIL), metacarpal III width (MIIIW), metacarpal IV length (MIVL), metacarpal IV width (MIVW), metacarpal V length (MVL), metacarpal V width (MVW), phalanx I length (PILL), measured as phalanx II length (PIIL), phalanx III length (PIIL), phalanx IV length (PIVL), phalanx V length (PVL). In addition, the hand index (HI) was calculated. Logistic Regression (LR), Random Forest (RF), Linear Discriminant Analysis (LDA), K-nearest neighbour (KNN) and Naive Bayes (NB) were used as MLAs. In the study, the KNN algorithm's Accuracy, SEN, F1 and Specificity ratios were determined as 88 %. In this study using MLA, it is understood that the highest accuracy belongs to the KNN algorithm. Except for the hand's MIIW, MIIIW, MIVW, MVW, HI variables, other variables were statistically significant in terms of sex difference.


En el estudio, el objetivo era predecir el sexo a partir de mediciones manuales utilizando algoritmos de aprendizaje automático (MLA). Las mediciones se realizaron en imágenes de RM de 60 hombres y 60 mujeres. Parámetros determinados; longitud de la mano (HL), longitud de la palma (PL), ancho de la mano (HW), ancho de la muñeca (EBG), longitud del metacarpiano I (MIL), ancho del metacarpiano I (MIW), longitud del metacarpiano II (MIIL), ancho del metacarpiano II (MIIW), longitud del metacarpiano III (MIIL), ancho del metacarpiano III (MIIIW), longitud del metacarpiano IV (MIVL), ancho del metacarpiano IV (MIVW), longitud del metacarpiano V (MVL), ancho del metacarpiano V (MVW), longitud de la falange I (PILL), medido como longitud de la falange II (PIIL), longitud de la falange III (PIIL), longitud de la falange IV (PIVL), longitud de la falange V (PVL). Además, se calculó el índice de la mano (HI). Regresión logística (LR), Random Forest (RF), Análisis discriminante lineal (LDA), K-vecino más cercano (KNN) y Naive Bayes (NB) se utilizaron como MLA. En el estudio, las proporciones de precisión, SEN, F1 y especificidad del algoritmo KNN se determinaron en un 88 %. En este estudio que utiliza MLA, se entiende que la mayor precisión pertenece al algoritmo KNN. Excepto por las variables MIIW, MIIIW, MIVW, MVW, HI de la mano, otras variables fueron estadísticamente significativas en términos de diferencia de sexo.


Subject(s)
Humans , Male , Female , Carpal Bones/diagnostic imaging , Finger Phalanges/diagnostic imaging , Metacarpal Bones/diagnostic imaging , Sex Determination by Skeleton/methods , Algorithms , Magnetic Resonance Imaging , Carpal Bones/anatomy & histology , Discriminant Analysis , Logistic Models , Finger Phalanges/anatomy & histology , Metacarpal Bones/anatomy & histology , Machine Learning , Random Forest
11.
J Nippon Med Sch ; 90(2): 141-148, 2023.
Article in English | MEDLINE | ID: mdl-37258255

ABSTRACT

Posttraumatic malunion with combination of angular, rotational, and shortening deformity of the proximal phalanx may cause scissoring of a finger and impairment of hand function. Cosmetic disfigurement and severe dysfunction of fingers require surgical correction, most often via open corrective osteotomies and rigid fixation with a plate or screws. However, such an approach requires a longer incision, inevitably results in a scar, and has a higher potential for extensor tendon adhesion. Also, abruption of the periosteum and plating of the phalange requires longer bone healing time. Thus, we devised a technique of minimally invasive correction of phalangeal malunion using an external mini-fixator. We presented representative three cases of malunited fractures of phalanges treated with the Ilizarov mini-fixator in adolescence and review reports of similar cases. The usage of Ilizarov mini-fixator provided excellent outcomes for posttraumatic malunion of three fingers.


Subject(s)
Finger Phalanges , Fractures, Malunited , Humans , Adolescent , Fractures, Malunited/diagnostic imaging , Fractures, Malunited/surgery , Fracture Fixation, Internal , Finger Phalanges/diagnostic imaging , Finger Phalanges/surgery , Osteotomy/methods , Fingers
12.
Eur J Pediatr ; 182(6): 2785-2792, 2023 Jun.
Article in English | MEDLINE | ID: mdl-37016042

ABSTRACT

Hand fractures represent commonly encountered injuries in pediatric patients. However, due to modern means of mobility and product safety, the occurrence and distribution of these fractures have changed during the last decades. Therefore, it was the aim of this study to present an update of the epidemiology, pattern, and treatment of hand fractures in a large pediatric cohort. All patients aged between 0 and 17 years treated in our Department in 2019 with fractures of the phalanges, metacarpus, or carpus were included. The medical records were reviewed for age, gender, injury mechanism, fracture localization, season, and treatment. Patients were divided into three different age groups (0-5, 6-12, and 13-17 years). A total of 731 patients with 761 hand fractures were treated during the 1-year study period. The mean age was 11.1 ± 3.5 years, and the majority was male (65%). Male patients were significantly older compared to female patients (p = 0.008). Also, 78.7% of the fractures affected the phalanges, 17.6% the metacarpals, and 3.7% the carpal bones. The proximal phalanges were the most commonly fractured bones (41.5%). Patients with fractures of the carpus were significantly older compared to children sustaining fractures of the metacarpus or phalangeal bones (p < 0.001). Sixteen percent of our patients were treated surgically; these patients were significantly older compared to conservatively treated patients (p = 0.011).  Conclusion: The epidemiology, mechanisms of injury, distribution, and treatment of hand fractures significantly varies among different age groups. This knowledge is of importance for educational purposes of younger colleagues entrusted with care of children and adolescents as well as development of effective prevention strategies. What is Known: • Pediatric hand fractures represent the second most common fractures in children. • The epidemiology of pediatric hand fractures has changed during the last decades and therefore there is a need for an update regarding distribution and epidemiology of pediatric hand fractures. What is New: • In this retrospective cohort study, 761 pediatric hand fractures of 731 patients were analyzed in detail. • The main mechanisms of younger patients were entrapment injuries, older children most commonly sustained their fractures due to ball sport injuries. There was an increasing rate of metacarpal and carpal fractures with increasing age, and these fractures had to be treated operatively more often than phalangeal fractures.


Subject(s)
Finger Phalanges , Fractures, Bone , Hand Injuries , Metacarpal Bones , Child , Humans , Male , Adolescent , Female , Infant, Newborn , Infant , Child, Preschool , Retrospective Studies , Fractures, Bone/epidemiology , Fractures, Bone/etiology , Fractures, Bone/therapy , Metacarpal Bones/injuries , Finger Phalanges/diagnostic imaging , Finger Phalanges/injuries , Finger Phalanges/surgery , Hand Injuries/epidemiology , Hand Injuries/etiology , Hand Injuries/therapy
13.
Article in English | MEDLINE | ID: mdl-36877665

ABSTRACT

Osteoid osteoma (OO) is a benign osteoblastic bone tumor typically involving the diaphysis or metaphysis in long tubular bones. OO in phalanges of the great toe has been rarely reported, and it is often challenging to differentiate with subacute osteomyelitis, bone abscess, or osteoblastoma. This case report describes an uncommon case of a 13-year-old female patient with subperiosteal OO in the proximal phalanx of the great toe. The atypical location of OO should be familiarized to include appropriate differential diagnosis and to ensure accurate diagnosis by radiologic evaluations. Surgical excision remains the benchmark for the treatment of OO with its advantages on direct visualization and histologic confirmation for the diagnosis.


Subject(s)
Bone Neoplasms , Finger Phalanges , Hallux , Osteoma, Osteoid , Osteomyelitis , Soft Tissue Neoplasms , Female , Humans , Adolescent , Osteoma, Osteoid/diagnostic imaging , Osteoma, Osteoid/surgery , Hallux/diagnostic imaging , Hallux/surgery , Diaphyses , Finger Phalanges/diagnostic imaging , Finger Phalanges/surgery , Bone Neoplasms/diagnostic imaging , Bone Neoplasms/surgery
14.
J Pediatr Orthop ; 43(5): e363-e369, 2023.
Article in English | MEDLINE | ID: mdl-36914261

ABSTRACT

BACKGROUND: Treatment protocols for macrodactyly have not been elucidated due to its rarity and variety of clinical manifestations. This study aims to share our long-term clinical results of epiphysiodesis in children with macrodactyly. METHODS: A retrospective chart review was performed for 17 patients with isolated macrodactyly treated with epiphysiodesis over 20 years. Length and width of each phalanx in both the affected finger and the corresponding unaffected finger in the contralateral hand were measured. Results were presented in ratios of the affected to unaffected side for each phalanx. Measuring of length and width of phalanx was performed preoperatively and postoperatively at 6, 12, and 24 months, and the last follow-up session. Postoperative satisfaction scoring was done with visual analogue scale. RESULTS: The mean follow-up period was 7 years and 2 months. In the proximal phalanx, length ratio significantly decreased compared with preoperative state at after more than 24 months, in the middle phalanx after 6 months, in the distal phalanx after 12 months. When classified by the growth patterns, the progressive type showed significant decrease in length ratio at after 6 months, and the static type after 12 months. Patients were overall satisfied with the results. CONCLUSION: Epiphysiodesis effectively regulated longitudinal growth with different degree of control for different phalanges in the long-term follow-up.


Subject(s)
Finger Phalanges , Limb Deformities, Congenital , Humans , Child , Retrospective Studies , Fingers/surgery , Finger Phalanges/diagnostic imaging , Finger Phalanges/surgery
15.
Arch Orthop Trauma Surg ; 143(8): 5437-5444, 2023 Aug.
Article in English | MEDLINE | ID: mdl-36939892

ABSTRACT

INTRODUCTION: Osteoid osteoma (OO) is a common benign bone tumor. OO is observed most frequently in the long bones, especially in the tibia and femur. When occurring in the bones of the hand, OO can be a diagnostic and therapeutic challenge. The aim of this study was to provide a systematic review of occurrence, symptoms, diagnosis and treatment options regarding OO in hand bones. MATERIALS AND METHODS: We performed a systematic review of the literature. All studies from the online databases PubMed and SpringerLink, which reported cases of osteoid osteomas in the bones of the hand, were included. By summarizing the literature, we evaluated the localization within the hand as well as diagnostic and therapeutic options. RESULTS: We included 133 studies reporting 401 cases. OO was mostly common in the phalanges. The diagnosis was mostly made by CT (computed tomography) scan. Most of the OO were treated surgically by open curettage or en bloc resection. CONCLUSIONS: Osteoid osteomas in the bones of the hand are rare and a delayed diagnosis is common. In cases of pain combined with particular symptoms such as nail hypertrophy and swelling OO should be considered. Of the most used imaging methods, CT scans have the highest sensitivity.


Subject(s)
Bone Neoplasms , Finger Phalanges , Osteoma, Osteoid , Humans , Osteoma, Osteoid/diagnostic imaging , Osteoma, Osteoid/surgery , Hand/surgery , Pain , Finger Phalanges/diagnostic imaging , Finger Phalanges/surgery , Bone Neoplasms/diagnostic imaging , Bone Neoplasms/surgery
16.
J Hand Surg Asian Pac Vol ; 28(1): 117-120, 2023 Feb.
Article in English | MEDLINE | ID: mdl-36803333

ABSTRACT

Intraosseous schwannomas are extremely rare and only a few cases involving the proximal phalanx and metacarpal of the hand have been reported. We report a patient with an intraosseous schwannoma of the distal phalanx. Radiographs showed lytic lesions in the bony cortex and enlarged soft shadows of the distal phalanx. The lesion was hyperintense to fat on T2-weighted magnetic resonance imaging (MRI) and strongly enhanced after gadolinium (Gd) administration. Surgical findings revealed that the tumour had developed from the palmar side of the distal phalanx and the medullary cavity was filled with a yellow tumour. The histological diagnosis was schwannoma. A definitive diagnosis of intraosseous schwannoma using radiography is difficult. In our case, a high signal was observed on Gd-enhanced MRI and histological findings showed areas with a high cellular area. Thus, Gd-enhanced MRI may help in the diagnosis of intraosseous schwannomas of the hand. Level of Evidence: Level V (Therapeutic).


Subject(s)
Finger Phalanges , Neurilemmoma , Humans , Radiography , Magnetic Resonance Imaging/methods , Neurilemmoma/diagnostic imaging , Neurilemmoma/surgery , Neurilemmoma/pathology , Finger Phalanges/diagnostic imaging , Finger Phalanges/surgery , Finger Phalanges/pathology , Hand
17.
J Hand Surg Am ; 48(6): 627.e1-627.e5, 2023 06.
Article in English | MEDLINE | ID: mdl-36828763

ABSTRACT

Intramedullary headless compression screw fixation of proximal phalangeal fractures permits semirigid stabilization through a minimally invasive approach with negligible tendon disturbance, allowing early mobilization and rehabilitation. Antegrade insertion is preferred for basal fractures, but various concerns and technical difficulties have been identified with both intra- and transarticular instrumentation. We describe a technical tip to facilitate easier guidewire insertion and instrumentation with a screw via an intra-articular approach.


Subject(s)
Finger Phalanges , Fractures, Bone , Humans , Finger Phalanges/diagnostic imaging , Finger Phalanges/surgery , Fractures, Bone/diagnostic imaging , Fractures, Bone/surgery , Bone Screws , Fracture Fixation, Internal
18.
PeerJ ; 11: e14352, 2023.
Article in English | MEDLINE | ID: mdl-36643632

ABSTRACT

It has been recognized as early as the Victorian era that the apex of the distal phalanx has a distinct embryological development from the main shaft of the distal phalanx. Recent studies in regenerative medicine have placed an emphasis on the role of the apex of the distal phalanx in bone regrowth. Despite knowledge about the unique aspects of the distal phalanx, all phalanges are often treated as equivalent. Our morphological study reiterates and highlights the special anatomical and embryological properties of the apex of the distal phalanx, and names the apex "the bony cap" to distinguish it. We posit that the distal phalanx shaft is endochondral, while the bony cap is intramembranous and derived from the ectodermal wall. During development, the bony cap may be a separate structure that will fuse to the endochondral distal phalanx in the adult, as it ossifies well before the distal phalanges across taxa. Our study describes and revives the identity of the bony cap, and we identify it in three mammalian species: humans, cats, and horses (Homo sapiens, Felis catus domestica, and Equus caballus). During the embryonic period, we show the bony cap has a thimble-like shape that surrounds the proximal endochondral distal phalanx. The bony cap may thus play an inductive role in the differentiation of the corresponding nail, claw, or hoof (keratin structures) of the digit. When it is not present or develops erroneously, the corresponding keratin structures are affected, and regeneration is inhibited. By terming the bony cap, we hope to inspire more attention to its distinct identity and role in regeneration.


Subject(s)
Finger Phalanges , Hoof and Claw , Humans , Cats , Horses , Animals , Finger Phalanges/diagnostic imaging , Extremities , Hoof and Claw/diagnostic imaging , Mammals
19.
Minerva Pediatr (Torino) ; 75(4): 476-481, 2023 08.
Article in English | MEDLINE | ID: mdl-31129950

ABSTRACT

BACKGROUND: In epileptic patients with motor disability, it's difficult to disentangle the effects of antiepileptic drugs (AEDs) on bone health from those provoked by impaired mobility. The aim of this study was to evaluate the effects of AEDs on bone mineral status by phalangeal quantitative ultrasound (QUS), a no-radiation and non-invasive method, in pediatric patients with motor impairment and epilepsy. METHODS: We enrolled 56 patients (31 females, 25 males) with epilepsy and motor impairment and 24 children with only motor disability (13 females, 11 males). Patients were stratified by Gross Motor Function Classification System Scale (GMFCS) in 4 groups: group A1 with epilepsy and mild motor impairment (GMFCS levels I-II), group A2 with only mild motor impairment, group B1 with epilepsy and severe motor impairment (GMFCS levels III-V), group B2 with only severe motor impairment. The bone mineral status was evaluated by phalangeal QUS and amplitude-dependent speed of sound (AD-SoS) Z-score was calculated for each patient. RESULTS: The four groups showed no significant differences in age, gender and 25-hydroxyvitamin D levels. The group B1 had a statistically lower amplitude-dependent speed of sound Z-score as compared to group A2 (P<0.05). The multivariate analysis of independent factors revealed a significant correlation between amplitude-dependent speed of sound Z-score and Gross Motor Function Classification System levels (P=0.004). The mean Z-score value decreased by 0.53, increasing the motor impairment. CONCLUSIONS: The bone mineral status measured as AD-SoS strongly correlates with severity of motor disability evaluated by GMFCS as compared to antiepileptic therapy and 25-hydroxyvitamin D levels.


Subject(s)
Disabled Persons , Epilepsy , Finger Phalanges , Motor Disorders , Male , Female , Humans , Child , Anticonvulsants/adverse effects , Motor Disorders/etiology , Finger Phalanges/diagnostic imaging , Calcifediol , Epilepsy/drug therapy
20.
J Nippon Med Sch ; 89(6): 599-605, 2023 Feb 01.
Article in English | MEDLINE | ID: mdl-34526474

ABSTRACT

We present a case of solitary chondrosarcoma arising from the proximal phalanx of the ring finger in an elderly man. The chondrosarcoma developed over a period of 14 years, during which the phalanx became progressively more deformed. Several radiographic investigations were carried out, but the patient declined further suggested diagnostic examinations (computed tomography, magnetic resonance imaging, biopsy). Eventually, the lesion became significantly enlarged, and radiographs showed osteolytic lesions in the phalangeal bone. Ray amputation of the finger was required to establish a wide resection of the chondrosarcoma. Most osteochondral tumors arising from the phalanges are benign tumors such as enchondromas, but primary chondrogenic malignant bone tumors (chondrosarcomas) occasionally occur. Chondrosarcoma of the phalanx is difficult to distinguish from enchondroma of the phalanx, because histological investigations of the two neoplasms often produce similar findings. Even with a combination of clinical, biopsy, and imaging findings, differentiating these neoplasms is still challenging, because the characteristic clinical and radiological features of chondrosarcoma do not appear until it becomes aggressive and starts to cause destructive changes. Once that happens, radical expanded resection of the tumor is essential. Therefore, longstanding enchondroma-like lesions should be actively treated in elderly patients, even if a definite diagnosis of chondrosarcoma cannot be made.


Subject(s)
Bone Neoplasms , Chondroma , Chondrosarcoma , Finger Phalanges , Male , Humans , Aged , Bone Neoplasms/diagnostic imaging , Bone Neoplasms/surgery , Fingers/diagnostic imaging , Fingers/surgery , Fingers/pathology , Finger Phalanges/diagnostic imaging , Finger Phalanges/surgery , Chondrosarcoma/diagnostic imaging , Chondrosarcoma/surgery , Chondroma/diagnostic imaging , Chondroma/surgery
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